This course is an interdisciplinary course for undergraduates, postgraduates and relevant practitioners engaged in biomedical (engineering), clinical medicine, imaging, rehabilitation medicine, and stomatology (medicine), as well as medical devices and biomechanics. This course introduces the application status and prospect of mechanics, digital simulation (finite element analysis, etc.), reverse engineering, 3D printing and other technologies in the medical field from the perspective of engineering and medical integration, and specifically introduces the basic concepts and basic knowledge of various related fields. The present situation and development trend of 3d visualization technology in medical field are introduced. Taking MIMICs software as the background, this course focuses on the core technology of 3d reconstruction of human body -- the idea, process and method of 3d reconstruction of human body based on CT or MRI. Based on the established 3D model, this course further introduces the application of anatomic measurement, surgical planning, preoperative numerical simulation evaluation, rapid prototyping (3D printing) and other modules. The core purpose of the course is to bridge the gap between engineering and medicine and to lay the foundation for true integration of disciplines.