The course is structured as 3 blocks with case presentations of important Bacterial pathogens. The case presentations will cover the following areas:
1. Basic virulence strategies of bacterial, viral, and eukaryotic (fungal, parasite) pathogens, with a focus on the microbe. These include mechanisms of adherence, nutrient acquisition, growth and protein secretion.
2. Mechanisms by microbial pathogens use to target essential host cell processes. Topics include: invasion and intracellular survival, immune evasion, cytoskeletal disruption and disruption of cell adherence and migration.
3. Antimicrobial resistance and vaccines. How do different microbes (bacteria, fungi, parasites and viruses) overcome antimicrobial therapies/agents, and vaccine approaches? Problems associated with antimicrobial resistance and vaccine design, including current and novel approaches will we discussed.